SCHEMBL416484

SCHEMBL416484

O=S(=O)(c1ccc(O)cc1)c1ccc(OCc2ccc(Cl)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.56
MAOB P27338 6/20 0.55
MAOA P21397 2/20 0.55
ABCG2 Q9UNQ0 1/20 0.54
APP P05067 2/20 0.54
AR P10275 1/20 0.53
PKM P14618 2/20 0.51
GAA P10253 1/20 0.51
ALDH1A1 P00352 2/20 0.50
PTPRZ1 P23471 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
CYP2C19 P33261 1/20 0.50
PTGS2 P35354 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HIF1A Q16665 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51564 0.92 GAA (0.59) APPPKMGAAALDH1A1PTPRZ1
SCHEMBL6280745 0.92 GAA (0.59) APPPKMGAAALDH1A1PTPRZ1
SCHEMBL3624903 0.87 MAOB (0.69) NR4A2MAOBMAOAABCG2APP
SCHEMBL11600066 0.87 MAOB (0.69) NR4A2MAOBMAOAABCG2APP
SCHEMBL12769557 0.85 BCL2L1 (0.53) NR4A2MAOBMAOAAPPAR
SCHEMBL7753235 0.84 PKM (0.75) MAOBAPPPKMGAAALDH1A1
SCHEMBL420238 0.84 MAOB (0.56) MAOBAPPARPKMGAA
SCHEMBL419556 0.84 LMNA (0.73) NR4A2MAOBABCG2ARPKM
SCHEMBL10709540 0.84 RXRA (0.59) APPPKMGAAALDH1A1PTPRZ1
SCHEMBL5444737 0.82 MAOB (0.59) NR4A2MAOBMAOAAPPAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US claimed
US-12030328-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2024-07-09 US disclosed
WO-2023153481-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-08-17 WO disclosed
EP-4227107-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-08-16 EP disclosed
US-11649380-B2 Water-dispersible sheet NIPPON PAPER PAPYLIA CO., LTD. (JP) 2023-05-16 US disclosed
US-20230147446-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2023-05-11 US disclosed
EP-4126557-A1 THERMOSENSITIVE RECORDING MEDIUM AND METHOD FOR PRODUCING THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2023-02-08 EP disclosed
US-20220153052-A1 THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2022-05-19 US disclosed
EP-3941756-A1 THERMOSENSITIVE RECORDING MEDIUM Ricoh Company, Ltd. (JP) 2022-01-26 EP disclosed
US-11052694-B2 Water-dispersible sheet NIPPON PAPER PAPYLIA CO., LTD (JP) 2021-07-06 US disclosed
US-20060216537-A1 Coating paper which can be removed by water and a method for preparation thereof NIPPON PAPER PAPYLIA CO., LTD. (JP) 2006-09-28 US disclosed
EP-1705288-A2 A coating paper which can be removed by water and a method for preparation thereof Nippon Paper Industries Co., Ltd. (JP) 2006-09-27 EP disclosed
EP-0559525-B2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO LTD (JP) 2001-02-07 EP disclosed
EP-0559525-B1 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO LTD (JP) 1997-11-05 EP disclosed
US-5296441-A Having heat sensitive layer containing monoetherified dihydroxyphenyl sulfone developer, aluminum hydroxide TOMOEGAWA PAPER CO., LTD. (JP) 1994-03-22 US disclosed
EP-0559525-A2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO. LTD. (JP) 1993-09-08 EP disclosed
US-5102693-A Calendering intermediate layer to smooth surface, coating onto support and forming a thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1992-04-07 US disclosed
US-4975408-A INTERMEDIATE INSULATING LAYER HAVING SURFACE SMOOTHNESS GIVING IMPROVED COLORING SENSITIVITY; FOAMED LAYER HAVING MINUTE VOIDS RICOH COMPANY, LTD. (JP) 1990-12-04 US disclosed
US-4912079-A Thermosensitive coloring layer RICOH COMPANY, LTD. (JP) 1990-03-27 US disclosed
US-4895828-A INTERMEDIATE EXPANDED PLASTIC FILLER LAYER AND ELECTROCONDUCTIVE MATERIAL RICOH COMPANY, LTD. (JP) 1990-01-23 US disclosed