SCHEMBL3625875

SCHEMBL3625875

FC(C(F)(F)F)C(F)(F)COc1cc(Cl)ncn1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
AAK1 Q2M2I8 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3618782 0.89 HDAC1 (0.38) HDAC1HDAC6HDAC5AAK1
SCHEMBL21538308 0.83
SCHEMBL20993991 0.83 CYP1A2 (0.42) AAK1
SCHEMBL558551 0.81 HDAC1 (0.43) HDAC1HDAC6HDAC5AAK1
SCHEMBL3661090 0.79
SCHEMBL21538340 0.77 ALDH1A1 (0.37) HDAC1HDAC6HDAC5
SCHEMBL5400995 0.75 HDAC1 (0.38) HDAC1HDAC6HDAC5AAK1
SCHEMBL30365655 0.74 HDAC1 (0.35) HDAC1HDAC6HDAC5
SCHEMBL5394558 0.74 NUDT1 (0.42) HDAC1HDAC6HDAC5AAK1
SCHEMBL3626254 0.74 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190327970-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-10-31 US disclosed
WO-2010119878-A1 PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-21 WO disclosed
WO-2010119878-A1 PYRIMIDINE COMPOUND AND ITS USE FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190327970-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROLLING AGENT CONTAINING SAME DDT, ACHE, NISCH HDAC1 1710/4885HDAC6 1025/4885HDAC5 2199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.