Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362228 | 0.91 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL364180 | 0.83 | GPBAR1 (0.35) | — | |
| SCHEMBL364217 | 0.81 | GPBAR1 (0.30) | — | |
| SCHEMBL364971 | 0.80 | GPBAR1 (0.31) | — | |
| SCHEMBL364143 | 0.79 | FFAR1 (0.35) | ALDH1A1 | |
| SCHEMBL363805 | 0.78 | GPBAR1 (0.31) | — | |
| SCHEMBL364263 | 0.78 | GPBAR1 (0.31) | — | |
| SCHEMBL362932 | 0.78 | RAB9A (0.33) | — | |
| SCHEMBL364539 | 0.77 | POLB (0.32) | — | |
| SCHEMBL364836 | 0.77 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | claimed |
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |