Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 14/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364833 | 0.85 | KCNN4 (0.36) | KCNN4NPC1RAB9AKCNE1KCNQ1 | |
| SCHEMBL362616 | 0.85 | POLB (0.34) | KCNN4 | |
| SCHEMBL364814 | 0.84 | KCNN4 (0.43) | KCNN4NPC1RAB9AKCNE1KCNQ1 | |
| SCHEMBL363771 | 0.83 | NPC1 (0.42) | NPC1RAB9AMEN1ALDH1A1MAPT | |
| SCHEMBL13927993 | 0.83 | KCNN4 (0.51) | KCNN4NPC1RAB9AKCNE1KCNQ1 | |
| SCHEMBL364193 | 0.79 | NPC1 (0.34) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL363549 | 0.79 | NPC1 (0.34) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL363211 | 0.79 | NPC1 (0.34) | NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL14965778 | 0.77 | RAB9A (0.37) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL14965530 | 0.77 | RAB9A (0.37) | NPC1RAB9AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |