SCHEMBL3626022

SCHEMBL3626022

CCCCCCCCCCCCC(CCC)OP(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.67
PTPN1 P18031 1/20 0.53
FDPS P14324 5/20 0.52
S1PR2 O95136 5/20 0.49
S1PR1 P21453 5/20 0.49
S1PR3 Q99500 5/20 0.49
S1PR4 O95977 4/20 0.49
LAP3 P28838 2/20 0.48
LPAR3 Q9UBY5 4/20 0.47
LPAR1 Q92633 3/20 0.47
LPAR2 Q9HBW0 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3632792 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL27486860 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL29758198 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL3624518 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL14368863 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL10690779 1.00 SMPD1 (0.67) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL28982704 0.98 SMPD1 (0.65) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL3629609 0.98 SMPD1 (0.65) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL3631672 0.98 SMPD1 (0.65) SMPD1PTPN1FDPSS1PR2S1PR1
SCHEMBL4941232 0.98 SMPD1 (0.63) SMPD1PTPN1FDPSS1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1633440-A Branched-chain lipophilic molecule derivatives and uses thereof DPHARM LTD (IL) 2005-06-29 CN claimed
EP-1305322-A4 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF DPHARM LTD (IL) 2005-04-13 EP claimed
JP-2004505898-A 2004-02-26 JP claimed
US-20030186897-A1 Derivatives of branched-chain lipophilic molecules and uses thereof D-PHARM, LTD. (IL) 2003-10-02 US claimed
EP-1305322-A2 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF D-Pharm Ltd. (IL) 2003-05-02 EP claimed
WO-2002011666-A2 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF D-PHARM LTD. (IL) 2002-02-14 WO claimed
CN-119258567-A Radioactive organic waste liquid rectifying device and rectifying method 中核四川环保工程有限责任公司 2025-01-07 CN disclosed
US-7687483-B2 Derivatives of branch-chain lipophilic molecular and uses thereof D-PHARM LTD. (IL) 2010-03-30 US disclosed
EP-1305322-B1 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF DPHARM LTD (IL) 2010-01-13 EP disclosed
US-20070135381-A1 Derivatives of branch-chain lipophilic molecular and uses thereof D-PHARM LTD. (IL) 2007-06-14 US disclosed
US-7186703-B2 Derivatives of branched-chain lipophilic molecules and uses thereof D-PHARM LTD. (IL) 2007-03-06 US disclosed
CN-1633440-A Branched-chain lipophilic molecule derivatives and uses thereof DPHARM LTD (IL) 2005-06-29 CN disclosed
EP-1305322-A4 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF DPHARM LTD (IL) 2005-04-13 EP disclosed
US-20030186897-A1 Derivatives of branched-chain lipophilic molecules and uses thereof D-PHARM, LTD. (IL) 2003-10-02 US disclosed
EP-1305322-A2 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF D-Pharm Ltd. (IL) 2003-05-02 EP disclosed
WO-2002011666-A2 DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF D-PHARM LTD. (IL) 2002-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135381-A1 Derivatives of branch-chain lipophilic molecular and uses thereof PLIN3, GLS, LIPG SMPD1 172/4885PTPN1 3868/4885FDPS 624/4885
US-20030186897-A1 Derivatives of branched-chain lipophilic molecules and uses thereof PLIN3, PLIN5, SLC27A1 SMPD1 415/4885PTPN1 3060/4885FDPS 957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.