SCHEMBL3626499

SCHEMBL3626499

O=Cc1ccc(C=Nc2cccc(S)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.53
CA1 P00915 9/20 0.53
CA9 Q16790 8/20 0.53
CA7 P43166 6/20 0.53
PTGS2 P35354 5/20 0.42
PTGS1 P23219 2/20 0.42
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ACHE P22303 4/20 0.37
MAOB P27338 1/20 0.37
CA12 O43570 2/20 0.36
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626498 1.00 CA2 (0.53) CA2CA1CA9CA7PTGS2
SCHEMBL14196493 0.77 PTGS2 (0.59) CA2CA1CA9CA7PTGS2
SCHEMBL14327704 0.75 CA2 (0.55) CA2CA1CA9CA7PTGS2
SCHEMBL9827450 0.72 ALDH1A1 (0.47) CA2CA1CA9PTGS2ALDH1A1
SCHEMBL2958301 0.71
SCHEMBL863217 0.71
SCHEMBL29956149 0.71
SCHEMBL24194096 0.69 CA1 (0.53) CA2CA1CA9CA7PTGS2
SCHEMBL11326747 0.69 CA1 (0.52) CA2CA1CA9CA7PTGS2
SCHEMBL14351426 0.69 ALDH1A1 (0.52) CA2CA1CA9PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010136820-A1 NOVEL PHOTOVOLTAIC AND PHOTOELECTROCHEMICAL COATINGS AND DEVICES BANGOR UNIVERSITY (GB) 2010-12-02 WO disclosed