⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275147 | 0.81 | NOS1 (0.42) | — | |
| SCHEMBL8934735 | 0.73 | — | — | |
| SCHEMBL18773921 | 0.71 | CA2 (0.38) | — | |
| SCHEMBL63173 | 0.71 | — | — | |
| SCHEMBL3626499 | 0.71 | CA2 (0.53) | — | |
| SCHEMBL3626498 | 0.71 | CA2 (0.53) | — | |
| SCHEMBL942161 | 0.70 | — | — | |
| SCHEMBL942655 | 0.70 | — | — | |
| SCHEMBL8739557 | 0.70 | — | — | |
| SCHEMBL11346166 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288373-B2 | Modulators of CXCR7 | CHEMOCENTRYX, INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20120103220-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | SONOKAWA KOJI (JP) | 2012-05-03 | — | — | US | disclosed |
| US-8142982-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |
| US-8142978-B2 | Planographic printing plate precursor and printing method using the same | FUJIFILM CORPORATION (JP) | 2012-03-27 | — | — | US | disclosed |
| US-8113116-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-02-14 | — | — | US | disclosed |
| US-7994338-B2 | An enzyme in the tryptophan degradation pathway, used to treat neurodegenerative disorders, certain cancers, drug addiction; 2-sulfonamido-substituted oxazole, imidazole or thiazole compounds such as 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-dimethylaminomethyl-1,3-thiazole-2-yl]benzenesulfonamide | THE J. DAVID GLADSTONE INSTITUTES (US) | 2011-08-09 | — | — | US | disclosed |
| US-20110014121-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20100150831-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20090246696-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090111049-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | FUJIFILM CORPORATION (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20090047601-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20080286685-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2008-11-20 | — | — | US | disclosed |
| US-7393094-B2 | Ink for inkjet, ink set for inkjet, and inkjet recording method | FUJIFILM CORPORATION (JP) | 2008-07-01 | — | — | US | disclosed |
| US-20080070905-A1 | SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE | J. DAVID GLADSTONE INSTITUTES | 2008-03-20 | — | — | US | disclosed |