Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362753 | 0.87 | TRPV1 (0.34) | TRPV1SORT1MAPTSMN1; SMN2 | |
| SCHEMBL362550 | 0.87 | TRPV1 (0.34) | TRPV1SORT1MAPTSMN1; SMN2 | |
| SCHEMBL363211 | 0.85 | NPC1 (0.34) | TRPV1SORT1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL364193 | 0.85 | NPC1 (0.34) | TRPV1SORT1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL363549 | 0.85 | NPC1 (0.34) | TRPV1SORT1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL364536 | 0.79 | SORT1 (0.35) | TRPV1SORT1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL362712 | 0.78 | SORT1 (0.34) | SORT1ALDH1A1KDM4E | |
| SCHEMBL364587 | 0.78 | SORT1 (0.34) | SORT1ALDH1A1KDM4E | |
| SCHEMBL363084 | 0.78 | SORT1 (0.34) | SORT1ALDH1A1KDM4E | |
| SCHEMBL371147 | 0.77 | SORT1 (0.34) | SORT1MAPTSMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |