Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363549 | 0.88 | NPC1 (0.34) | SORT1ALDH1A1WNT3ATRPV1CYP2D6 | |
| SCHEMBL364193 | 0.88 | NPC1 (0.34) | SORT1ALDH1A1WNT3ATRPV1CYP2D6 | |
| SCHEMBL363211 | 0.88 | NPC1 (0.34) | SORT1ALDH1A1WNT3ATRPV1CYP2D6 | |
| SCHEMBL364311 | 0.86 | POLB (0.31) | SORT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL362323 | 0.81 | KCNN4 (0.41) | SORT1ALDH1A1WNT3AKMO | |
| SCHEMBL362720 | 0.80 | SORT1 (0.33) | SORT1ALDH1A1TSHRCYP2D6CYP1A2 | |
| SCHEMBL363181 | 0.79 | HDAC3 (0.38) | SORT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL362869 | 0.79 | TRPV1 (0.38) | SORT1ALDH1A1TRPV1CYP2D6CYP1A2 | |
| SCHEMBL364587 | 0.78 | SORT1 (0.34) | SORT1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL362712 | 0.78 | SORT1 (0.34) | SORT1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |