Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051037 | 0.90 | ADRB2 (0.54) | ADRB2ADRB3MAPK1ADRB1DRD2 | |
| SCHEMBL7051039 | 0.90 | ADRB2 (0.54) | ADRB2ADRB3MAPK1ADRB1DRD2 | |
| SCHEMBL9360727 | 0.81 | MEN1 (0.49) | KMT2AMAPTMEN1ALDH1A1ADRB2 | |
| SCHEMBL10661432 | 0.80 | ADRB2 (0.49) | KMT2AMAPTMEN1ADRB2ADRB3 | |
| SCHEMBL2174086 | 0.80 | KMT2A (0.44) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL2174081 | 0.80 | KMT2A (0.44) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL2182547 | 0.80 | KMT2A (0.44) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL13074414 | 0.79 | KMT2A (0.42) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL1134236 | 0.79 | KMT2A (0.42) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL29368044 | 0.79 | KMT2A (0.42) | KMT2AMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128355-A2 | IMPROVED PROCESSES FOR PREPARING SUBSTANTIALLY PURE ARFORMOTEROL AND ITS INTERMEDIATES | ACTAVIS GROUP PTC EHF (IS) | 2010-11-11 | — | — | WO | disclosed |