Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051037 | 0.91 | ADRB2 (0.54) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL7051039 | 0.91 | ADRB2 (0.54) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL10661432 | 0.89 | ADRB2 (0.49) | MEN1KMT2ACTSVCTSLADRB3 | |
| SCHEMBL9360806 | 0.85 | ADRB2 (0.53) | ADRB3ADRB1ADRB2ADRA1DADRA1A | |
| SCHEMBL3628731 | 0.81 | KMT2A (0.46) | MEN1KMT2AALDH1A1CTSVCTSL | |
| SCHEMBL7149471 | 0.80 | ADRA1D (0.51) | KMT2AADRB3ADRB1ABCB1ADRB2 | |
| SCHEMBL7149467 | 0.80 | ADRA1D (0.51) | KMT2AADRB3ADRB1ABCB1ADRB2 | |
| SCHEMBL11083174 | 0.80 | ADRA1D (0.51) | KMT2AADRB3ADRB1ABCB1ADRB2 | |
| SCHEMBL7150543 | 0.79 | ADRB1 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7150621 | 0.79 | ADRB2 (0.62) | ADRB3ADRB1ADRB2CASP3CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390762-B1 | New bronchospasmolytic compounds and process for their preparation | DRACO AB (SE) | 1994-01-19 | — | — | EP | disclosed |
| EP-0390762-A1 | New bronchospasmolytic compounds and process for their preparation | Aktiebolaget Draco (SE) | 1990-10-03 | — | — | EP | disclosed |