Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | BRS3 | P32247 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6179887 | 0.98 | LTB4R2 (0.56) | LTB4R2TAAR1HNF4ABCAT2MYC | |
| SCHEMBL500761 | 0.86 | BCAT2 (0.67) | LTB4R2TAAR1BCAT2 | |
| SCHEMBL5151244 | 0.85 | LTB4R2 (0.60) | LTB4R2HNF4ABRS3LPAR1FOLH1 | |
| SCHEMBL19237016 | 0.85 | CFD (0.50) | LTB4R2HNF4ABCAT2MYCBRS3 | |
| SCHEMBL27461455 | 0.85 | TAAR1 (0.48) | LTB4R2TAAR1BCAT2LPAR1 | |
| SCHEMBL30292805 | 0.84 | HNF4A (0.63) | LTB4R2HNF4ABCAT2MYCFNTA | |
| SCHEMBL18759613 | 0.84 | HNF4A (0.63) | LTB4R2HNF4ABCAT2MYCFNTA | |
| Hydrochloric Acid SCHEMBL500203 | 0.84 | BCAT2 (0.65) | LTB4R2TAAR1BCAT2 | |
| SCHEMBL27907961 | 0.84 | TAAR1 (0.47) | LTB4R2TAAR1HNF4ABCAT2 | |
| SCHEMBL27431910 | 0.84 | LTB4R2 (0.49) | LTB4R2TAAR1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | claimed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | claimed |
| WO-2015141958-A1 | COMPOUND BINDING TO PPARG BUT NOT ACTING AS PROMOTER AND PHARMACEUTICAL COMPOSITION FOR TREATING PPARG-RELATED DISEASES CONTAINING SAME AS ACTIVE INGREDIENT | 현대약품 주식회사 | 2015-09-24 | — | — | WO | disclosed |
| EP-2146963-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | Theravance, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008133896-A2 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS | THERAVANCE, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |
| CN-1787833-A | Pharmaceutical preparation comprising acid-stabilized insulin | NOVO NORDISK AS (DK) | 2006-06-14 | — | — | CN | disclosed |
| CN-1064042-C | Intermediate of benzazepine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1058710-C | New benzamide derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1040748-C | Benzazepine derivatives, pharmaceutical compositions and intermediates thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-11-18 | — | — | CN | disclosed |
| EP-0612317-A1 | SUBSTITUTED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0572455-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | Astra Pharmaceuticals Limited (GB) | 1993-12-08 | — | — | EP | disclosed |
| US-5256695-A | Acyl amidine and acyl guanidine substituted biphenyl derivatives | E. R. SQUIBB & SONS, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5256781-A | Anticholesterol, antilipemic, hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| US-5236925-A | Hypotensive agents, treatment of congestive heart failure | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |
| WO-1993008170-A1 | SUBSTITUTED HETEROCYCLES AS ANGIOTENSIN II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| US-5187168-A | Hypotensive agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |
| US-5177097-A | Acyl amidine and acyl, guanidine substituted biphenyl derivatives | E. R. SQUIBB & SONS, INC. (US) | 1993-01-05 | — | — | US | disclosed |
| WO-1992014714-A1 | SUBSTITUTED PYRIDINONES AND PYRIMIDINONES AS ANGIOTENSIN II ANTAGONISTS | FISONS PLC (GB) | 1992-09-03 | — | — | WO | disclosed |