Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A20 | O43772 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631222 | 0.93 | SLC25A20 (0.36) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL3631227 | 0.93 | SLC25A20 (0.36) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL4638950 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL2693658 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL905579 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL2695073 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL60425 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL418811 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL60847 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 | |
| SCHEMBL62053 | 0.85 | SMPD1 (0.47) | SLC25A20TP53TSHRCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687483-B2 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2010-03-30 | — | — | US | disclosed |
| EP-1305322-B1 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2010-01-13 | — | — | EP | disclosed |
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2007-06-14 | — | — | US | disclosed |
| US-7186703-B2 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM LTD. (IL) | 2007-03-06 | — | — | US | disclosed |
| EP-1305322-A4 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2005-04-13 | — | — | EP | disclosed |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM, LTD. (IL) | 2003-10-02 | — | — | US | disclosed |
| EP-1305322-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-Pharm Ltd. (IL) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002011666-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-PHARM LTD. (IL) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | PLIN3, GLS, LIPG | SLC25A20 843/4885TP53 442/4885TSHR 2714/4885 |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | PLIN3, PLIN5, SLC27A1 | SLC25A20 770/4885TP53 250/4885TSHR 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.