Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519928 | 0.84 | CTSD (0.38) | MEN1KMT2ATDP1CTSDCA1 | |
| Hydrochloric Acid SCHEMBL6686934 | 0.81 | BLM (0.39) | MEN1KMT2ATDP1CTSDCA1 | |
| SCHEMBL17714568 | 0.80 | MEN1 (0.42) | MEN1KMT2ATDP1SIGMAR1PTPRF | |
| SCHEMBL3957272 | 0.78 | MAOA (0.47) | ALDH1A1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL6960151 | 0.77 | MAOA (0.50) | TDP1ALDH1A1MAOAMAOB | |
| SCHEMBL29943903 | 0.76 | KDM4E (0.46) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL2957138 | 0.76 | ALDH1A1 (0.45) | KMT2ATDP1ALDH1A1CFTRHSD17B10 | |
| SCHEMBL2956029 | 0.76 | KDM4E (0.46) | MEN1KMT2ATDP1CA1CA2 | |
| SCHEMBL7121807 | 0.76 | F2 (0.41) | KMT2ACTSDCA1CA2CA9 | |
| SCHEMBL7120827 | 0.75 | CTSD (0.42) | CTSDCA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146984-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008144380-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |