Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519928 | 0.85 | CTSD (0.38) | CTSDCA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6686934 | 0.83 | BLM (0.39) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL8219059 | 0.79 | CTSD (0.58) | CTSDCA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30046012 | 0.78 | CTSD (0.56) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL279655 | 0.78 | ALDH1A1 (0.53) | CA1CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL22343535 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2KDM4ELMNAPDK1 | |
| SCHEMBL7129881 | 0.77 | AKR1C3 (0.57) | ALDH1A1HSD17B10LMNAAKR1C3POLB | |
| SCHEMBL7121807 | 0.77 | F2 (0.41) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL3957272 | 0.75 | MAOA (0.47) | ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL3630278 | 0.75 | MEN1 (0.41) | CTSDCA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667356-B2 | Including an n-amidinobenzamide derivative; heat aging resistance | BRIDGESTONE CORPORATION (JP) | 2003-12-23 | — | — | US | disclosed |
| US-20030134947-A1 | Containing imine, amidine or guanidine antioxidants to improve heat aging resistance; may be substituted by acyl, thioacyl or additional imine groups | BRIDGESTONE CORPORATION, OTSUKA CHEMICAL CO., LTD. | 2003-07-17 | — | — | US | disclosed |
| US-6515055-B1 | Excellent in heat aging resistance due to addition of compounds exemplified by N'-(N-benzoylamidino) benzoic acid hydrazide | BRIDGESTONE CORPORATION (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-1101793-A1 | Heat ageing resistant rubber composition | Bridgestone Corporation (JP) | 2001-05-23 | — | — | EP | disclosed |