Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748798 | 0.97 | MEN1 (0.56) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL30533691 | 0.97 | MEN1 (0.56) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL27083061 | 0.95 | MEN1 (0.55) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL18191933 | 0.92 | HDAC1 (0.47) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL18191924 | 0.92 | HDAC1 (0.47) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL18191928 | 0.92 | HDAC1 (0.47) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL18191937 | 0.92 | HDAC1 (0.47) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL3630767 | 0.90 | HDAC3 (0.46) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL9075242 | 0.90 | MEN1 (0.50) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL12527752 | 0.90 | HDAC1 (0.49) | MEN1KMT2AMAPTTHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687483-B2 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2010-03-30 | — | — | US | disclosed |
| EP-1305322-B1 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2010-01-13 | — | — | EP | disclosed |
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | D-PHARM LTD. (IL) | 2007-06-14 | — | — | US | disclosed |
| US-7186703-B2 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM LTD. (IL) | 2007-03-06 | — | — | US | disclosed |
| EP-1305322-A4 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | DPHARM LTD (IL) | 2005-04-13 | — | — | EP | disclosed |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | D-PHARM, LTD. (IL) | 2003-10-02 | — | — | US | disclosed |
| EP-1305322-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-Pharm Ltd. (IL) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002011666-A2 | DERIVATIVES OF BRANCHED-CHAIN LIPOPHILIC MOLECULES AND USES THEREOF | D-PHARM LTD. (IL) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135381-A1 | Derivatives of branch-chain lipophilic molecular and uses thereof | PLIN3, GLS, LIPG | MEN1 2491/4885KMT2A 4828/4885MAPT 4774/4885 |
| US-20030186897-A1 | Derivatives of branched-chain lipophilic molecules and uses thereof | PLIN3, PLIN5, SLC27A1 | MEN1 2233/4885KMT2A 4607/4885MAPT 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.