Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NNMT | P40261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363964 | 0.80 | GPR183 (0.38) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL365148 | 0.79 | SMN1; SMN2 (0.38) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL2316036 | 0.77 | KCNN4 (0.53) | KCNN4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12187544 | 0.76 | NPC1 (0.41) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL3523419 | 0.76 | KCNN4 (0.58) | KCNN4KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL38656126 | 0.74 | NNMT (0.49) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL22285418 | 0.73 | NNMT (0.47) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL22079377 | 0.73 | NNMT (0.48) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL363777 | 0.71 | KMT2A (0.39) | NPC1RAB9ANNMTKMT2AMEN1 | |
| SCHEMBL31292187 | 0.70 | BRS3 (0.50) | NPC1RAB9ANNMTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |