Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GPR183 | P32249 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363964 | 0.87 | GPR183 (0.38) | SMN1; SMN2GPR183RAB9AALDH1A1MAPT | |
| SCHEMBL14894794 | 0.87 | GPR183 (0.38) | SMN1; SMN2GPR183RAB9AALDH1A1MAPT | |
| SCHEMBL363152 | 0.79 | KCNN4 (0.45) | SMN1; SMN2RAB9AALDH1A1MAPTHTT | |
| SCHEMBL363254 | 0.75 | TDO2 (0.36) | SMN1; SMN2GPR183RAB9AALDH1A1MAPT | |
| SCHEMBL364183 | 0.74 | GPR183 (0.34) | SMN1; SMN2GPR183RAB9AALDH1A1MAPT | |
| SCHEMBL13427579 | 0.72 | KCNN4 (0.48) | SMN1; SMN2RAB9AALDH1A1MAPTHTT | |
| SCHEMBL364659 | 0.72 | KCNK3 (0.33) | RAB9AALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL14965127 | 0.71 | KMT2A (0.38) | SMN1; SMN2RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL14965530 | 0.67 | RAB9A (0.37) | RAB9AMAPTMAPK1KMT2APOLB | |
| SCHEMBL14965778 | 0.67 | RAB9A (0.37) | RAB9AMAPTMAPK1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |