Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 9/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365351 | 0.83 | CYP19A1 (0.31) | KCNN4FFAR1CYP19A1 | |
| SCHEMBL370104 | 0.83 | RAB9A (0.33) | FFAR1HDAC6HDAC1HDAC3 | |
| SCHEMBL16222433 | 0.73 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1HDAC6HDAC1 | |
| SCHEMBL13427540 | 0.72 | KCNN4 (0.69) | KCNN4KCNE1KCNQ1HDAC6HDAC1 | |
| SCHEMBL371335 | 0.70 | RAB9A (0.32) | — | |
| SCHEMBL13427561 | 0.70 | KCNN4 (0.72) | KCNN4KCNE1KCNQ1 | |
| SCHEMBL3523419 | 0.70 | KCNN4 (0.58) | KCNN4HDAC6HDAC1HDAC3HDAC4 | |
| SCHEMBL365204 | 0.69 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL363061 | 0.69 | KCNN4 (0.34) | KCNN4 | |
| SCHEMBL362087 | 0.69 | ALDH1A1 (0.31) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |