Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371335 | 0.88 | RAB9A (0.32) | RAB9AHTTALDH1A1KMT2ANPC1 | |
| SCHEMBL363201 | 0.83 | KCNN4 (0.38) | HDAC3HDAC1HDAC6FFAR1 | |
| SCHEMBL370651 | 0.78 | HDAC1 (0.32) | RAB9AHTTALDH1A1HDAC3HDAC1 | |
| SCHEMBL362592 | 0.69 | KCNN4 (0.37) | RAB9AALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL365351 | 0.68 | CYP19A1 (0.31) | FFAR1 | |
| SCHEMBL362323 | 0.67 | KCNN4 (0.41) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL363549 | 0.67 | NPC1 (0.34) | RAB9AALDH1A1NPC1MAPTNPSR1 | |
| SCHEMBL364193 | 0.67 | NPC1 (0.34) | RAB9AALDH1A1NPC1MAPTNPSR1 | |
| SCHEMBL363211 | 0.67 | NPC1 (0.34) | RAB9AALDH1A1NPC1MAPTNPSR1 | |
| SCHEMBL364659 | 0.66 | KCNK3 (0.33) | RAB9AALDH1A1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |