Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370104 | 0.88 | RAB9A (0.33) | RAB9ANPC1HTTALDH1A1MEN1 | |
| SCHEMBL370651 | 0.81 | HDAC1 (0.32) | RAB9ANPC1HTTALDH1A1GPBAR1 | |
| SCHEMBL363201 | 0.70 | KCNN4 (0.38) | — | |
| SCHEMBL363181 | 0.68 | HDAC3 (0.38) | ALDH1A1 | |
| SCHEMBL362087 | 0.68 | ALDH1A1 (0.31) | RAB9AALDH1A1NPSR1 | |
| SCHEMBL363084 | 0.65 | SORT1 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL365148 | 0.65 | SMN1; SMN2 (0.38) | RAB9ANPC1HTTALDH1A1MEN1 | |
| SCHEMBL362323 | 0.65 | KCNN4 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL362592 | 0.65 | KCNN4 (0.37) | RAB9ANPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL362430 | 0.65 | RAB9A (0.34) | RAB9ANPC1HTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |