SCHEMBL3632780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7224310	0.77	CYP1A2 (0.56)	CYP1A2NCF1KDM4EHTTLMNA
	SCHEMBL7998749	0.76	CYP1A2 (0.60)	CYP1A2NCF1KDM4EHTTUSP2
	SCHEMBL4059622	0.74	KDM4E (0.53)	KDM4EHTTMEN1KMT2AL3MBTL1
	SCHEMBL2528435	0.72	NCF1 (0.49)	CYP1A2NCF1KDM4EHTTLMNA
	SCHEMBL15562148	0.72	ALDH1A1 (0.44)	CYP1A2ALDH1A1CYP2C19
	SCHEMBL7379490	0.72	CYP1A2 (0.55)	CYP1A2NCF1KDM4EHTTUSP2
	SCHEMBL6629887	0.72	SMN1; SMN2 (0.49)	KDM4EHTTMEN1KMT2ASMN1; SMN2
	SCHEMBL6634649	0.72	KDM4E (0.50)	KDM4EHTTLMNAMAPK1MEN1
	SCHEMBL21316068	0.72	CYP1A2 (0.58)	CYP1A2NCF1KDM4EHTTUSP2
	SCHEMBL5935677	0.71	CYP1A2 (0.49)	CYP1A2NCF1KDM4EHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.