Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835204 | 0.72 | NR4A2 (0.55) | BACE1PDE3AMEN1KMT2A | |
| SCHEMBL19477394 | 0.68 | SLC6A2 (0.37) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3225927 | 0.67 | MEN1 (0.41) | BACE1SLC6A2SLC6A3SLC6A4MEN1 | |
| SCHEMBL3971157 | 0.66 | PDE5A (0.35) | — | |
| SCHEMBL7441662 | 0.64 | HTR3A (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3327779 | 0.63 | PRKCD (0.48) | — | |
| SCHEMBL3321416 | 0.63 | ACHE (0.54) | KMT2A | |
| SCHEMBL3320135 | 0.62 | NMT1 (0.48) | — | |
| SCHEMBL3321755 | 0.62 | HRH3 (0.47) | — | |
| SCHEMBL3322501 | 0.61 | ALDH1A1 (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155748-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008144268-A1 | UROTENSIN II RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-27 | — | — | WO | disclosed |