SCHEMBL3320135

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3321755	0.89	HRH3 (0.47)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3322417	0.88	HRH3 (0.49)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3320637	0.88	HRH3 (0.49)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3633687	0.87	ALDH1A1 (0.45)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3324396	0.85	CYP1A2 (0.46)	ALDH1A1CYP3A4CYP2D6CYP1A2CLK4
	SCHEMBL3320791	0.84	HTR1A (0.43)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3667245	0.83	ALDH1A1 (0.42)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3319966	0.83	ACHE (0.48)	ALDH1A1CYP3A4CYP2D6CYP1A2CLK4
	SCHEMBL3316840	0.83	ALDH1A1 (0.42)	NMT1ALDH1A1CYP3A4CYP2D6CYP1A2
	SCHEMBL3322228	0.83	ACHE (0.47)	ALDH1A1CYP3A4CYP2D6CYP1A2CLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.