SCHEMBL3633788

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25790166	0.92	PKM (0.59)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL25788217	0.89	PKM (0.53)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL679796	0.87	PKM (0.61)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL25788226	0.84	TSHR (0.59)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL848890	0.82	KMT2A (0.60)	PLA2G4B
	SCHEMBL927230	0.81	PKM (0.62)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL9578562	0.81	PKM (0.53)	PKMTSHRTP53PLA2G4BALDH1A1
	Hydrochloric Acid SCHEMBL8058585	0.81	RARB (0.60)	PKMTSHRTP53PLA2G4BALDH1A1
	SCHEMBL4872013	0.81	RARB (0.59)	PKMTSHRTP53PLA2G4BRARB
	SCHEMBL118037	0.80	PKM (0.77)	PKMTSHRTP53PLA2G4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.