Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.74 |
| ▸ | SHBG | P04278 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.74 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.63 |
| ▸ | PGR | P06401 | 3/20 | 0.63 |
| ▸ | HRH1 | P35367 | 1/20 | 0.63 |
| ▸ | FNTA | P49354 | 3/20 | 0.60 |
| ▸ | FNTB | P49356 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cortisone SCHEMBL14862166 | 0.89 | HSD17B10 (0.69) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL4545 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL4323075 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL5188889 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL13026141 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL23975175 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL14373312 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL19327146 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL10598529 | 0.88 | NR3C1 (1.00) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 | |
| Fludrocortisone SCHEMBL1333577 | 0.88 | NR3C1 (0.80) | NR3C1HSD17B10SERPINA6SHBGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146653-A2 | MEDICAL DEVICES AND PROCEDURES FOR ASSESSING A LUNG AND TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE | Portaero, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008140989-A2 | MEDICAL DEVICES AND PROCEDURES FOR ASSESSING A LUNG AND TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE | PORTAERO, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| WO-1989008119-A1 | HIGH MOLECULAR WEIGHT PRODRUG DERIVATIVES OF ANTI-INFLAMMATORY DRUGS | SELCH LARSEN CLAUS (DK) | 1989-09-08 | — | — | WO | disclosed |