Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.83 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.83 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.83 |
| ▸ | DRD4 | P21917 | 1/20 | 0.63 |
| ▸ | AKT1 | P31749 | 1/20 | 0.63 |
| ▸ | AKT2 | P31751 | 1/20 | 0.63 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665096 | 0.91 | OPRM1 (1.00) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL8863557 | 0.86 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| Oxalic Acid SCHEMBL5778025 | 0.86 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| Hydrochloric Acid SCHEMBL5386933 | 0.84 | CYP2D6 (0.65) | OPRM1OPRK1OPRL1DRD4CYP2D6 | |
| SCHEMBL5777954 | 0.84 | OPRM1 (0.77) | OPRM1OPRK1OPRL1DRD4CYP2D6 | |
| SCHEMBL11223608 | 0.84 | OPRM1 (0.86) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL3636230 | 0.83 | OPRM1 (0.69) | OPRM1OPRK1OPRL1CHRM1 | |
| SCHEMBL6404540 | 0.83 | PLD1 (0.81) | OPRM1OPRK1OPRL1DRD4CYP2D6 | |
| SCHEMBL5379395 | 0.83 | HSD11B1 (0.66) | OPRM1OPRK1OPRL1CYP2D6CYP2C9 | |
| SCHEMBL24709114 | 0.82 | CYP2D6 (0.74) | OPRM1OPRK1OPRL1DRD4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |