Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 10/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081455 | 0.80 | GHSR (0.66) | GHSRKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6636640 | 0.79 | GHSR (0.65) | GHSRKMT2APOLBALDH1A1GAA | |
| SCHEMBL1514721 | 0.78 | KMT2A (0.70) | GHSRKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL315915 | 0.77 | GHSR (0.63) | GHSRKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL316283 | 0.77 | GHSR (0.62) | GHSRKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL314979 | 0.77 | GHSR (0.62) | GHSRKMT2APOLBALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL317007 | 0.77 | GHSR (0.62) | GHSRKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL315422 | 0.76 | GHSR (0.61) | GHSRKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL316492 | 0.76 | GHSR (0.61) | GHSRKMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6461553 | 0.76 | GHSR (0.61) | GHSRKMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | claimed |
| US-20100093638-A1 | TREAMENT FOR CHEMICAL SUBSTANCE ADDICTION | ABUNON AB (SE) | 2010-04-15 | — | — | US | disclosed |
| EP-2155227-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | Dickson, Suzanne L (SE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009020419-A1 | NEW TREATMENT FOR CHEMICAL SUBSTANCE ADDICTION | DICKSON SUZANNE L (SE) | 2009-02-12 | — | — | WO | disclosed |
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089398-A1 | Isoxazole carboxamide derivatives as ghrelin receptor modulators | GPR119, GIPR, GLP1R | GHSR 5/4885KMT2A 1793/4885POLB 4403/4885 |
| US-20100093638-A1 | TREAMENT FOR CHEMICAL SUBSTANCE ADDICTION | GHSR, GHRHR, TRHR | GHSR 1/4885KMT2A 1131/4885POLB 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.