Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310607 | 0.85 | NAMPT (0.47) | NAMPT | |
| SCHEMBL30711543 | 0.74 | QDPR (0.47) | QDPRMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL311751 | 0.71 | SIGMAR1 (0.37) | MAPTALDH1A1KDM4EGAA | |
| SCHEMBL15283571 | 0.70 | NAMPT (0.47) | QDPRNAMPT | |
| SCHEMBL24793986 | 0.69 | NAMPT (0.51) | QDPRNAMPTMAPTALDH1A1LMNA | |
| SCHEMBL2946035 | 0.69 | NAMPT (0.51) | QDPRNAMPTMAPTALDH1A1LMNA | |
| SCHEMBL29709692 | 0.69 | NAMPT (0.51) | QDPRNAMPTMAPTALDH1A1LMNA | |
| SCHEMBL28435175 | 0.69 | QDPR (0.46) | QDPRNAMPTMAPTMEN1KMT2A | |
| SCHEMBL17197280 | 0.69 | QDPR (0.54) | QDPRNAMPTMAPTMEN1KMT2A | |
| SCHEMBL3503856 | 0.69 | ALDH1A1 (0.32) | L3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162454-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2008150799-A1 | IMIDAZOPYRIDINE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-11 | — | — | WO | disclosed |