Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635465 | 0.97 | L3MBTL1 (0.37) | LMNASMN1; SMN2ATMPARP1HSD11B1 | |
| Hydrochloric Acid SCHEMBL9698155 | 0.95 | L3MBTL1 (0.35) | LMNASMN1; SMN2ATMPARP1HSD11B1 | |
| SCHEMBL23278023 | 0.82 | ATM (0.42) | LMNASMN1; SMN2ATMSIGMAR1 | |
| SCHEMBL4404464 | 0.80 | CYP1A2 (0.41) | LMNASMN1; SMN2ATMALDH1A1SIGMAR1 | |
| SCHEMBL28321078 | 0.80 | ATM (0.32) | SMN1; SMN2ATMPARP1L3MBTL1ALDH1A1 | |
| SCHEMBL4104348 | 0.80 | ATM (0.36) | ATMPARP1L3MBTL1ALDH1A1 | |
| SCHEMBL18123290 | 0.78 | LMNA (0.37) | LMNASMN1; SMN2ATM | |
| SCHEMBL1088468 | 0.78 | SIGMAR1 (0.37) | LMNASMN1; SMN2ATMSIGMAR1 | |
| SCHEMBL3314582 | 0.78 | LMNA (0.37) | LMNASMN1; SMN2ATM | |
| SCHEMBL2862694 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| CN-117343028-A | Ionic liquid electrolyte with wide window, and preparation method and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | claimed |
| CN-117343028-A | Ionic liquid electrolyte with wide window, and preparation method and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | disclosed |
| WO-2020258893-A1 | A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-12-30 | — | — | WO | disclosed |
| EP-2265585-B1 | AMINE AND ETHER COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2014-09-17 | — | — | EP | disclosed |
| US-20120142685-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2012-06-07 | — | — | US | disclosed |
| EP-2144909-A1 | [2, 6]NAPHTHYRIDINES USEFUL AS PROTEIN KINASE INHIBITORS | Novartis Ag (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008122615-A1 | [2, 6] NAPHTHYRIDINES USEFUL AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142685-A1 | ORGANIC COMPOUNDS | MARK1, PKN1, MARK2 | LMNA 2683/4885SMN1; SMN2 3821/4885ATM 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.