SCHEMBL4104348

SCHEMBL4104348

CC(O)(C(N)=O)N1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.36
PARP1 P09874 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4109208 0.98 ATM (0.35) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL2167672 0.80 ATM (0.33) ATM
SCHEMBL3634948 0.80 LMNA (0.36) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL3635465 0.78 L3MBTL1 (0.37) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL28321078 0.76 ATM (0.32) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL472332 0.76 ALDH1A1 (0.42) L3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL9698155 0.76 L3MBTL1 (0.35) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL4637388 0.74 L3MBTL1 (0.34) ATMPARP1L3MBTL1ALDH1A1
Carbamic Acid SCHEMBL15206061 0.73 ATM (0.42) ATMPARP1L3MBTL1ALDH1A1
SCHEMBL844602 0.71 ATM (0.32) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2001288-B1 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS SYNGENTA LTD (GB) 2015-06-24 EP disclosed
US-8420859-B2 Formulations SYNGENTA LIMITED (GB) 2013-04-16 US disclosed
US-20090227453-A1 FORUMLATIONS SYNGENTA LIMITED (GB) 2009-09-10 US disclosed
CN-101404879-A Process for producing lactamide compound, novel lactamide compound and preparation containing lactamide compound SYNGENTA LTD (GB) 2009-04-08 CN disclosed
EP-2001288-A2 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS Syngenta Limited (GB) 2008-12-17 EP disclosed
WO-2007107745-A2 PROCESS FOR PRODUCING LACTAMIDE COMPOUNDS, NEW LACTAMIDE COMPOUNDS AND FORMULATIONS CONTAINING LACTAMIDE COMPOUNDS SYNGENTA LIMITED (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227453-A1 FORUMLATIONS CBR3, NR1H3, NR2C2 ATM 3331/4885PARP1 4658/4885L3MBTL1 3454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.