SCHEMBL3635124

SCHEMBL3635124

CC(C)(C)c1ccnc(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25144303 0.85 HTT (0.33) TSHR
SCHEMBL30465794 0.77 CYP2A6 (0.34) CA2
SCHEMBL2029268 0.77 CYP2A6 (0.34) CA2
SCHEMBL8840123 0.77 NOS3 (0.32) CYP3A4TSHRCYP2C19CA2
SCHEMBL993753 0.77 CCR1 (0.38) CYP3A4TSHRCYP2C19
SCHEMBL22543805 0.76 ALOX5AP (0.33)
SCHEMBL27592575 0.76 NOS2 (0.40)
Ammonia Solution, Strong SCHEMBL28822904 0.76 CYP2A6 (0.33)
SCHEMBL25144093 0.76 ATR (0.30)
SCHEMBL9772791 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132310-A1 HIGH STRENGTH URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES ARKEMA FRANCE (FR) 2026-05-14 US claimed
US-10844254-B2 Urethane acrylate hybrid structure adhesives HERCULES LLC (US) 2020-11-24 US claimed
EP-3676303-A1 URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES Hercules LLC (US) 2020-07-08 EP claimed
US-10246481-B2 Bile acid derivatives and methods for synthesis and use CITY OF HOPE (US) 2019-04-02 US claimed
WO-2019046200-A1 URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES HERCULES LLC (US) 2019-03-07 WO claimed
US-20180319836-A1 BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE HOPE CITY (US) 2018-11-08 US claimed
US-20170233431-A1 BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE HOPE CITY (US) 2017-08-17 US claimed
US-20140206657-A1 BILE ACID ANALOG TGR5 AGONISTS CITY OF HOPE (US) 2014-07-24 US claimed
CN-101687120-B Method for direct elution of reactive18F fluoride ions from anion exchange resins in an organic medium suitable for radiolabelling, without any evaporation step, by using strong organic bases TRASIS S A 2013-12-18 CN claimed
EP-2164590-B1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S A (BE) 2013-03-06 EP claimed
EP-2164590-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES Trasis S.A. (BE) 2010-03-24 EP claimed
WO-2009003251-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S.A. (BE) 2009-01-08 WO claimed
US-20260132310-A1 HIGH STRENGTH URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES ARKEMA FRANCE (FR) 2026-05-14 US disclosed
US-20250188109-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF SLOAN KETTERING INSITUTE FOR CANCER RES (US) 2025-06-12 US disclosed
US-12227535-B2 Triterpene saponins, methods of synthesis and uses thereof SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH 2025-02-18 US disclosed
WO-2024160806-A1 HIGH STRENGTH URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES ARKEMA FRANCE (FR) 2024-08-08 WO disclosed
US-20070049620-A1 Cyclic tertiary amine compound SANKYO COMPANY, LIMITED (JP) 2007-03-01 US disclosed
EP-0147012-B1 METHOD AND APPARATUS FOR SEPARATING OXYGEN FROM A GASEOUS MIXTURE AQUANAUTICS CORPORATION (a Delaware corporation) (US) 1989-12-27 EP disclosed
EP-0147012-A2 Method and apparatus for separating oxygen from a gaseous mixture AQUANAUTICS CORPORATION (a Delaware corporation) (US) 1985-07-03 EP disclosed
US-4475994-A Method and apparatus for separating oxygen from a gaseous mixture MAXDEM INCORPORATED (US) 1984-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070049620-A1 Cyclic tertiary amine compound MYD88, IL5, BRD4 CYP3A4 680/4885TSHR 499/4885CYP2C19 658/4885
US-20250188109-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF LSS, CYP51A1, TLR7 CYP3A4 554/4885TSHR 3033/4885CYP2C19 1871/4885
US-12227535-B2 Triterpene saponins, methods of synthesis and uses thereof LSS, CYP51A1, TLR7 CYP3A4 617/4885TSHR 2842/4885CYP2C19 1902/4885
US-20170233431-A1 BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE NR1H4, GPBAR1, SLC10A1 CYP3A4 157/4885TSHR 669/4885CYP2C19 390/4885
US-10246481-B2 Bile acid derivatives and methods for synthesis and use NR1H4, GPBAR1, SLC10A1 CYP3A4 157/4885TSHR 669/4885CYP2C19 390/4885
US-20260132310-A1 HIGH STRENGTH URETHANE ACRYLATE HYBRID STRUCTURE ADHESIVES HSPB1, PTK2, ICAM1 CYP3A4 3653/4885TSHR 4670/4885CYP2C19 4420/4885
US-20140206657-A1 BILE ACID ANALOG TGR5 AGONISTS GPBAR1, NR1H4, SLC10A1 CYP3A4 505/4885TSHR 128/4885CYP2C19 1636/4885
US-20180319836-A1 BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE NR1H4, GPBAR1, SLC10A1 CYP3A4 157/4885TSHR 669/4885CYP2C19 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.