Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285642 | 0.87 | CXCR2 (0.60) | KMT2AMEN1CXCR2FABP4MAPT | |
| SCHEMBL28289321 | 0.84 | KDM4E (0.64) | KMT2AMEN1NPC1RAB9ACXCR2 | |
| SCHEMBL3364068 | 0.82 | POLB (0.60) | KMT2AMEN1CXCR2FABP4MAPT | |
| SCHEMBL15698772 | 0.81 | MAP2K1 (0.56) | KMT2AMEN1NPC1RAB9ACXCR2 | |
| SCHEMBL2406195 | 0.81 | MAPT (0.62) | KMT2AMEN1CXCR2FABP4MAPT | |
| SCHEMBL21312751 | 0.80 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL29220911 | 0.80 | FABP4 (0.68) | KMT2AMEN1CXCR2FABP4MAPT | |
| SCHEMBL7573159 | 0.79 | CXCR2 (0.47) | KMT2AMEN1CXCR2ALBALDH1A1 | |
| SCHEMBL24021598 | 0.79 | CLCN2 (0.61) | KMT2AMEN1ALBFABP4MAPT | |
| SCHEMBL11542345 | 0.79 | CXCR2 (0.53) | KMT2AMEN1CXCR2FABP4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9946847-B2 | Libraries of compounds having desired properties and methods for making and using them | BIOBLOCKS INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150269356-A1 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS INC (US) | 2015-09-24 | — | — | US | disclosed |
| US-20150269356-A1 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS INC (US) | 2015-09-24 | — | — | US | disclosed |
| WO-2014047463-A2 | LIBRARIES OF COMPOUNDS HAVING DESIRED PROPERTIES AND METHODS FOR MAKING AND USING THEM | BIOBLOCKS, INC. (US) | 2014-03-27 | — | — | WO | disclosed |
| EP-2148862-A1 | DIHYDROQUINONE AND DIHYDRONAPHTHRIDINE INHIBITORS OF JNK | F. Hoffmann-Roche AG (CH) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008138920-A1 | DIHYDROQUINONE AND DIHYDRONAPHTHRIDINE INHIBITORS OF JNK | F. HOFFMANN-LA ROCHE AG (CH) | 2008-11-20 | — | — | WO | disclosed |
| US-4168312-A | Quinolone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-09-18 | — | — | US | disclosed |