Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.60 |
| ▸ | FABP4 | P15090 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406195 | 0.89 | MAPT (0.62) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL29220911 | 0.88 | FABP4 (0.68) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL3636604 | 0.87 | KMT2A (0.54) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL11542345 | 0.87 | CXCR2 (0.53) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL3364068 | 0.87 | POLB (0.60) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL11543358 | 0.87 | ALDH1A1 (0.57) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL2445505 | 0.84 | CXCR2 (0.46) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL17060022 | 0.84 | CYP3A4 (0.60) | CXCR2MEN1KMT2AALDH1A1GFER | |
| SCHEMBL17350393 | 0.82 | CXCR2 (0.49) | CXCR2FABP4MAPTMEN1KMT2A | |
| SCHEMBL6269693 | 0.82 | MAPT (0.49) | CXCR2FABP4MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247641-B2 | Compounds, derivatives, compositions, preparation and uses | MGI GP, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7247641-B2 | Compounds, derivatives, compositions, preparation and uses | MGI GP, INC. (US) | 2007-07-24 | — | — | US | disclosed |
| WO-2005053609-A2 | METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 2005-06-16 | — | — | WO | disclosed |
| WO-2003014121-A9 | COMPOUNDS, DERIVATIVES, COMPOSITIONS, PREPARATION AND USES | GUILFORD PHARM INC (US) | 2004-03-25 | — | — | WO | disclosed |
| WO-2003014121-A1 | COMPOUNDS, DERIVATIVES, COMPOSITIONS, PREPARATION AND USES | GUILFORD PHARMACEUTICALS INC. (US) | 2003-02-20 | — | — | WO | disclosed |