Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277843 | 0.87 | MEN1 (0.57) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28276372 | 0.87 | KDM4E (0.65) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28277826 | 0.87 | ACLY (0.55) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8285642 | 0.87 | CXCR2 (0.60) | ALDH1A1HPGDKDM4ECXCR2KMT2A | |
| SCHEMBL28182473 | 0.86 | CXCR2 (0.55) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28278349 | 0.84 | ALDH1A1 (0.69) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL28276373 | 0.84 | POLB (0.48) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL8555568 | 0.84 | PTGS2 (0.71) | POLBALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL3636604 | 0.82 | KMT2A (0.54) | ALDH1A1KDM4ECXCR2KMT2AMEN1 | |
| SCHEMBL22719750 | 0.81 | MEN1 (0.60) | ALDH1A1KMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516946-A | A method of preparing carbazole compound | 上海交通大学 | 2019-03-26 | — | — | CN | claimed |
| CN-109516963-A | A method of preparing 1,2- dihydro-(4H) -3,1- benzoxazin-4-one compound | 上海交通大学 | 2019-03-26 | — | — | CN | disclosed |
| CN-109516946-A | A method of preparing carbazole compound | 上海交通大学 | 2019-03-26 | — | — | CN | disclosed |
| EP-2928880-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-14 | — | — | EP | disclosed |
| WO-2014021571-A1 | CARBAZOLE-BASED COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2014-02-06 | — | — | WO | disclosed |
| CN-102307857-A | High penetration compositions and their use | CHONGXI YU | 2012-01-04 | — | — | CN | disclosed |
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
| US-4417059-A | COLOR FORMERS FOR CARBONLESS DUPLICATING AND THERMAL MARKING | STERLING DRUG INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4343493-A | LEUCO DYES; CARBON-FREE; PRESSURE SENSITIVE ELEMENTS; THERMOSENSITIVITY | STERLING DRUG INC. (US) | 1982-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | POLB 2404/4885ALDH1A1 1558/4885HPGD 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.