Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A known ✓ | Q14432 | 2/20 | 0.50 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 10/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | OTC | P00480 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490730 | 0.82 | LMNA (0.44) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL16701801 | 0.78 | ALDH1A1 (0.56) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL726737 | 0.78 | — | — | |
| Phosphoric Acid SCHEMBL6761813 | 0.78 | ALDH1A1 (0.56) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL8649777 | 0.78 | ALDH1A1 (0.56) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL1978724 | 0.78 | ALDH1A1 (0.56) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL2537120 | 0.74 | ALDH1A1 (0.53) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoramidic Acid SCHEMBL6242351 | 0.74 | — | — | |
| Phosphoric Acid SCHEMBL11359032 | 0.74 | ALDH1A1 (0.53) | FDPSLMNAPDE3AADRB3PDE4D | |
| Phosphoric Acid SCHEMBL28878972 | 0.74 | ALDH1A1 (0.53) | FDPSLMNAPDE3AADRB3PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121781-A1 | FINE-PARTICULATE POLYMER DISPERSIONS COMPRISING STARCH | BASF SE (DE) | 2009-11-25 | — | — | EP | claimed |
| WO-2008071688-A1 | FINE-PARTICULATE POLYMER DISPERSIONS COMPRISING STARCH | BASF SE (DE) | 2008-06-19 | — | — | WO | claimed |
| US-20220372407-A1 | Detergent Compositions and Uses of the Same | NOVOZYMES A/S (DK) | 2022-11-24 | — | — | US | disclosed |
| EP-3440180-B1 | DETERGENT COMPOSITIONS AND USES OF THE SAME | NOVOZYMES AS (DK) | 2020-11-11 | — | — | EP | disclosed |
| US-10829721-B2 | Particulate composition | NOVOZYMES A/S (DK) | 2020-11-10 | — | — | US | disclosed |
| US-20200325418-A1 | DETERGENT COMPOSITIONS AND USES OF THE SAME | NOVOZYMES A/S (DK) | 2020-10-15 | — | — | US | disclosed |
| EP-3440180-A2 | DETERGENT COMPOSITIONS AND USES OF THE SAME | Novozymes A/S (DK) | 2019-02-13 | — | — | EP | disclosed |
| WO-2017174769-A2 | DETERGENT COMPOSITIONS AND USES OF THE SAME | NOVOZYMES A/S (DK) | 2017-10-12 | — | — | WO | disclosed |
| US-20140206593-A1 | Particulate Composition | NOVOZYMES A/S (DK) | 2014-07-24 | — | — | US | disclosed |
| EP-2158278-A1 | AQUEOUS DISPERSIONS OF (METH)ACRYLIC ESTERS OF POLYMERS CONTAINING N-HYDROXYALKYLATED LACTAM UNITS, AND USE OF (METH)ACRYLIC ESTERS OF POLYMERS CONTAINING N-HYDROXYALKYLATED LACTAM UNITS | Basf Se (DE) | 2010-03-03 | — | — | EP | disclosed |
| EP-2121781-A1 | FINE-PARTICULATE POLYMER DISPERSIONS COMPRISING STARCH | BASF SE (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008142003-A1 | AQUEOUS DISPERSIONS OF (METH)ACRYLIC ESTERS OF POLYMERS CONTAINING N-HYDROXYALKYLATED LACTAM UNITS, AND USE OF (METH)ACRYLIC ESTERS OF POLYMERS CONTAINING N-HYDROXYALKYLATED LACTAM UNITS | BASF SE (DE) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008071688-A1 | FINE-PARTICULATE POLYMER DISPERSIONS COMPRISING STARCH | BASF SE (DE) | 2008-06-19 | — | — | WO | disclosed |