Phosphoric Acid

Phosphoric Acid

SCHEMBL16701801

NCCN.NCCN.O=P(O)(O)O

nearest known ligand 0.56

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB3 known ✓ P13945 1/20 0.45
ALDH1A1 P00352 1/20 0.56
LMNA P02545 3/20 0.50
BLM P54132 2/20 0.50
CYP3A4 P08684 1/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
GABBR2 O75899 5/20 0.45
GABBR1 Q9UBS5 5/20 0.45
FDPS P14324 3/20 0.45
PDE3A Q14432 2/20 0.45
PDE4D Q08499 1/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
THPO P40225 1/20 0.45
ANPEP P15144 1/20 0.42
ERAP2 Q6P179 1/20 0.42
OTC P00480 1/20 0.42
KDM4E B2RXH2 1/20 0.40
MMP2 P08253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL8649777 1.00 ALDH1A1 (0.56) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL726737 1.00
Phosphoric Acid SCHEMBL6761813 1.00 ALDH1A1 (0.56) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL1978724 1.00 ALDH1A1 (0.56) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL27976521 0.96 ALDH1A1 (0.53) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL11359032 0.96 ALDH1A1 (0.53) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL28088006 0.96 ALDH1A1 (0.53) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL28878972 0.96 ALDH1A1 (0.53) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL2537120 0.96 ALDH1A1 (0.53) ALDH1A1LMNABLMCYP3A4NFKB1
Phosphoric Acid SCHEMBL6931735 0.92 ALDH1A1 (0.50) ALDH1A1LMNABLMCYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11433005-B2 Dental filling material and dental polymerizable composition GC CORPORATION (JP) 2022-09-06 US disclosed
US-11292968-B2 Sulfenamides as flame retardants SONGWON INTERNATIONAL AG (CH) 2022-04-05 US disclosed
CN-110872384-B Flame retardant composition, use thereof and method for the production thereof 松原国际股份有限公司 2022-02-25 CN disclosed
EP-3878900-A1 SULFENAMIDE FLAME RETARDANTS Songwon Industrial Co., Ltd. (KR) 2021-09-15 EP disclosed
EP-3066153-B1 SULFENAMIDES AS FLAME RETARDANTS SONGWON INT AG (CH) 2020-05-06 EP disclosed
US-20160289566-A1 SULFENAMIDES AS FLAME RETARDANTS SONGWON INTERNATIONAL AG (CH) 2016-10-06 US disclosed
EP-3066153-A1 SULFENAMIDES AS FLAME RETARDANTS SONGWON INTERNATIONAL AG (CH) 2016-09-14 EP disclosed
WO-2015067736-A1 SULFENAMIDES AS FLAME RETARDANTS WILÉN CARL-ERIC (FI) 2015-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289566-A1 SULFENAMIDES AS FLAME RETARDANTS STS, TST, PFAS ADRB3 4125/4885ALDH1A1 430/4885LMNA 4217/4885
US-11433005-B2 Dental filling material and dental polymerizable composition CAD, MEP1A, ESD ADRB3 4485/4885ALDH1A1 1384/4885LMNA 2093/4885
US-11292968-B2 Sulfenamides as flame retardants STS, TST, PFAS ADRB3 4125/4885ALDH1A1 430/4885LMNA 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.