Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632655 | 0.79 | GAA (0.55) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL3014389 | 0.79 | MC4R (0.45) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL3633209 | 0.77 | MEN1 (0.43) | MEN1KMT2APOLBGAAMAPT | |
| SCHEMBL3408856 | 0.72 | MC4R (0.48) | MEN1KMT2AGAAKCNQ2CYP2D6 | |
| SCHEMBL2344486 | 0.72 | MC4R (0.48) | MEN1KMT2AGAAKCNQ2CYP2D6 | |
| SCHEMBL311252 | 0.72 | TP53 (0.49) | MEN1KMT2APOLBALDH1A1CYP2C19 | |
| SCHEMBL8538901 | 0.72 | TP53 (0.49) | MEN1KMT2APOLBALDH1A1CYP2C19 | |
| SCHEMBL12536783 | 0.70 | TSHR (0.79) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL938198 | 0.69 | TP53 (0.68) | MEN1KMT2AMAPTALDH1A1CYP2C19 | |
| SCHEMBL72682 | 0.69 | TP53 (0.68) | MEN1KMT2AMAPTALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155706-A2 | REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY | Actavis Group PTC EHF (IS) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009004485-A2 | REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY | ACTAVIS GROUP PTC EHF (IS) | 2009-01-08 | — | — | WO | disclosed |