Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3014389 | 0.80 | MC4R (0.45) | MEN1KMT2ACYP2C19PKMAPEX1 | |
| SCHEMBL28304115 | 0.79 | KCNQ2 (0.44) | MEN1KMT2ACYP2C19POLBGAA | |
| SCHEMBL3636883 | 0.77 | MEN1 (0.51) | MEN1KMT2ACYP2C19PKMAPEX1 | |
| SCHEMBL10635605 | 0.73 | ABCC8 (0.55) | MEN1KMT2APKMPOLBGAA | |
| SCHEMBL3408856 | 0.73 | MC4R (0.48) | MEN1KMT2AGAACYP2D6KCNQ2 | |
| SCHEMBL2344486 | 0.73 | MC4R (0.48) | MEN1KMT2AGAACYP2D6KCNQ2 | |
| Pyrovalerone SCHEMBL4937421 | 0.73 | SLC6A3 (0.70) | SLC6A3SLC6A4SLC6A2 | |
| Pyrovalerone SCHEMBL4937392 | 0.73 | SLC6A3 (0.70) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10671931 | 0.73 | ABCC8 (0.57) | KMT2ACYP2C19PKMPOLBGAA | |
| SCHEMBL10680796 | 0.72 | ABCC8 (0.55) | KMT2ACYP2C19PKMPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155706-A2 | REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY | Actavis Group PTC EHF (IS) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009004485-A2 | REPAGLINIDE SUBSTANTIALLY FREE OF DIMER IMPURITY | ACTAVIS GROUP PTC EHF (IS) | 2009-01-08 | — | — | WO | disclosed |