Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536085 | 0.81 | IDO1 (0.56) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL1295195 | 0.78 | TAAR1 (0.55) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL5254359 | 0.77 | IDO1 (0.52) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL467216 | 0.77 | TAAR1 (0.54) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL467238 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRCALM1 | |
| Bromide SCHEMBL10874061 | 0.76 | IDO1 (0.50) | IDO1CA12CA1CA2CA7 | |
| Water SCHEMBL10445073 | 0.76 | TAAR1 (0.52) | IDO1CA12CA1CA2CA7 | |
| SCHEMBL1006647 | 0.75 | TAAR1 (0.55) | IDO1AGXTTAAR1MAOBCMA1 | |
| SCHEMBL7161828 | 0.75 | CALM1 (0.56) | IDO1TAAR1ALOX15CALM1MAOB | |
| SCHEMBL9294762 | 0.74 | CALM1 (0.55) | IDO1TAAR1ALOX15CALM1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| WO-2025242747-A1 | MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | WO | disclosed |
| US-20240391871-A1 | SUBSTITUTED HYDROXYMETHYL PYRROLIDINES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2024-11-28 | — | — | US | disclosed |
| EP-4405333-A1 | SUBSTITUTED HYDROXYMETHYL PYRROLIDINES AND MEDICAL USES THEREOF | Atrogi AB (SE) | 2024-07-31 | — | — | EP | disclosed |
| CN-118215652-A | Substituted hydroxymethyl pyrrolidines and medical uses thereof | 阿托基公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-118184703-A | Synthesis method of alpha-substituted chiral phosphonate compound | 中国人民解放军军事科学院防化研究院 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023046885-A1 | SUBSTITUTED HYDROXYMETHYL PYRROLIDINES AND MEDICAL USES THEREOF | ATROGI AB (SE) | 2023-03-30 | — | — | WO | disclosed |
| CN-112574011-A | One-pot synthesis method of substituted indane compounds | 武汉工程大学 | 2021-03-30 | — | — | CN | disclosed |
| EP-3207367-B1 | METHOD FOR MASS SPECTROMETRY ANALYSIS, COMPOUNDS AND KIT USEFUL THEREFOR | LUMIPROBE GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| EP-3072897-B1 | SPIROKETAL DERIVATIVES AND USE THEREOF AS DIABETIC MEDICINE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-06-26 | — | — | EP | disclosed |
| EP-0063799-B1 | 1-(3-(6-FLUORO-1,2-BENZISOXASOL-3-YL)PROPYL)-4-HYDROXY-4-PHENYLPIPERIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-11-27 | — | — | EP | disclosed |
| US-4543257-A | PENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1985-09-24 | — | — | US | disclosed |
| US-4416887-A | ANALGESICS; ANTIPSYCHOTIC AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4415581-A | ANALGESICS; PSYCHOLOGICAL DISORDERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4396770-A | ANALGESICS, PSYCHOSIS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0063799-A2 | 1-(3-(6-fluoro-1,2-benzisoxasol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-11-03 | — | — | EP | disclosed |
| US-4267188-A | USEFUL AS ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4176196-A | Hypoglycemic arylcyclohexane acetic acids | PFIZER INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4070541-A | Diarylmethylenes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |
| US-3936493-A | Diarylmethylenes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391871-A1 | SUBSTITUTED HYDROXYMETHYL PYRROLIDINES AND MEDICAL USES THEREOF | CYP3A5, PRMT5, CYP11B2 | IDO1 1705/4885CA12 3429/4885CA1 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.