SCHEMBL3637623

SCHEMBL3637623

C=CCc1cccc(OC(=O)C(CC(=O)O)S(=O)(=O)O)c1CC=C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.34
ELANE P08246 2/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 2/20 0.34
SRD5A1 P18405 2/20 0.33
PTGDR Q13258 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
ADRB2 P07550 1/20 0.33
HTR1A P08908 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CASP1 P29466 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3637619 0.92 MAPT (0.34) KDM4EELANEMAPTSMN1; SMN2ALDH1A1
SCHEMBL15048641 0.89 KDM4E (0.41) KDM4EELANEALDH1A1ADRB2HTR1A
Ether SCHEMBL4785780 0.83 ALDH1A1 (0.40) KDM4EELANESMN1; SMN2ALDH1A1ADRB2
Ether SCHEMBL2872980 0.82 ALDH1A1 (0.39) KDM4EELANESMN1; SMN2ALDH1A1ADRB2
SCHEMBL15048640 0.80 ADRB2 (0.41) KDM4EALDH1A1ADRB2HTR1AMEN1
SCHEMBL4785783 0.78 KDM4E (0.40) KDM4EALDH1A1ADRB2HTR1ATDP1
SCHEMBL5179050 0.78 GABRA1 (0.42) KDM4EELANEMAPTSMN1; SMN2ALDH1A1
SCHEMBL5179047 0.76 GABRA1 (0.43) KDM4EELANEMAPTSMN1; SMN2ALDH1A1
SCHEMBL18141022 0.76 KMT2A (0.40) KDM4EMAPTSMN1; SMN2ALDH1A1MEN1
SCHEMBL28245082 0.75 KMT2A (0.39) KDM4EMAPTSMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053093-B1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD FOR PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 EP disclosed
US-9234097-B2 Aqueous dispersion of polyamide rubber elastic body and method of producing the same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2016-01-12 US disclosed
US-20130150508-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD OF PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2013-06-13 US disclosed
US-20100234499-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD OF PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-09-16 US disclosed
EP-2053093-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD FOR PRODUCING THE SAME Sumitomo Seika Chemicals CO. LTD. (JP) 2009-04-29 EP disclosed