SCHEMBL3637619

SCHEMBL3637619

C=CCc1cccc(OC(=O)CC(C(=O)Oc2cccc(CC=C)c2CC=C)S(=O)(=O)O)c1CC=C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.34
ADRB2 P07550 4/20 0.34
ADRB1 P08588 3/20 0.34
LMNA P02545 3/20 0.34
HTR1A P08908 2/20 0.34
ADRB3 P13945 1/20 0.34
ADRA2C P18825 1/20 0.34
SLC6A2 P23975 1/20 0.34
BDKRB2 P30411 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
KCNH2 Q12809 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
KDM4E B2RXH2 4/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3637623 0.92 KDM4E (0.34) MAPTADRB2HTR1AKDM4EGABRA1
SCHEMBL15048640 0.89 ADRB2 (0.41) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL15048641 0.80 KDM4E (0.41) ADRB2ADRB1LMNAHTR1AADRB3
SCHEMBL5179047 0.77 GABRA1 (0.43) MAPTADRB2ADRB1LMNAHTR1A
SCHEMBL5179050 0.76 GABRA1 (0.42) MAPTKDM4EGABRA1GABRB2TDP1
SCHEMBL18141019 0.75 TSHR (0.37) MAPTTSHRKDM4EALDH1A1MEN1
SCHEMBL5914444 0.74 KDM4E (0.42) MAPTKDM4EGABRA1GABRB2ALDH1A1
Ether SCHEMBL5819722 0.74 ADRB2 (0.38) ADRB2ADRB1LMNAHTR1AADRB3
Ether SCHEMBL4785780 0.74 ALDH1A1 (0.40) ADRB2ADRB1LMNAHTR1AADRB3
Ether SCHEMBL2872980 0.74 ALDH1A1 (0.39) ADRB2ADRB1LMNAHTR1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053093-B1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD FOR PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 EP disclosed
US-9234097-B2 Aqueous dispersion of polyamide rubber elastic body and method of producing the same SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2016-01-12 US disclosed
US-20130150508-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD OF PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2013-06-13 US disclosed
US-20100234499-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD OF PRODUCING THE SAME SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-09-16 US disclosed
EP-2053093-A1 AQUEOUS DISPERSION OF POLYAMIDE RUBBER ELASTIC BODY AND METHOD FOR PRODUCING THE SAME Sumitomo Seika Chemicals CO. LTD. (JP) 2009-04-29 EP disclosed