Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.51 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.51 |
| ▸ | RPS17 | P08708 | 1/20 | 0.51 |
| ▸ | RPSA | P08865 | 1/20 | 0.51 |
| ▸ | RPS2 | P15880 | 1/20 | 0.51 |
| ▸ | RPL35A | P18077 | 1/20 | 0.51 |
| ▸ | RPL7 | P18124 | 1/20 | 0.51 |
| ▸ | RPL17 | P18621 | 1/20 | 0.51 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.51 |
| ▸ | RPS3 | P23396 | 1/20 | 0.51 |
| ▸ | RPS12 | P25398 | 1/20 | 0.51 |
| ▸ | RPL13 | P26373 | 1/20 | 0.51 |
| ▸ | RPL10 | P27635 | 1/20 | 0.51 |
| ▸ | RPL12 | P30050 | 1/20 | 0.51 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Florfenicol SCHEMBL49425 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL651770 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL3030994 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL29833609 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL4634861 | 0.99 | LMNA (0.97) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL650814 | 0.97 | LMNA (0.95) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL3817292 | 0.97 | LMNA (0.95) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL648260 | 0.96 | LMNA (0.93) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12683654 | 0.96 | LMNA (0.93) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL4421631 | 0.95 | LMNA (0.90) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155702-A1 | A PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | Schering-Plough Ltd. (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008150406-A1 | A PROCESS FOR PREPARING OXAZOLINE-PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH LTD. (CH) | 2008-12-11 | — | — | WO | disclosed |