Florfenicol

Florfenicol

SCHEMBL49425

CS(=O)(=O)c1ccc([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
CYP3A4 P08684 3/20 1.00
MEN1 O00255 1/20 1.00
KMT2A Q03164 1/20 1.00
TSHR P16473 2/20 0.78
RPLP1 P05386 1/20 0.51
RPLP0 P05388 1/20 0.51
RPS17 P08708 1/20 0.51
RPSA P08865 1/20 0.51
RPS2 P15880 1/20 0.51
RPL35A P18077 1/20 0.51
RPL7 P18124 1/20 0.51
RPL17 P18621 1/20 0.51
RPS4Y1 P22090 1/20 0.51
RPS3 P23396 1/20 0.51
RPS12 P25398 1/20 0.51
RPL13 P26373 1/20 0.51
RPL10 P27635 1/20 0.51
RPL12 P30050 1/20 0.51
RPL9; RPL9P7; RPL9P8; RPL9P9 P32969 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Florfenicol SCHEMBL651770 1.00 LMNA (1.00) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL3030994 1.00 LMNA (1.00) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL3637832 1.00 LMNA (1.00) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL29833609 1.00 LMNA (1.00) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL4634861 0.99 LMNA (0.97) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL650814 0.97 LMNA (0.95) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL3817292 0.97 LMNA (0.95) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL648260 0.96 LMNA (0.93) LMNACYP3A4MEN1KMT2ATSHR
SCHEMBL12683654 0.96 LMNA (0.93) LMNACYP3A4MEN1KMT2ATSHR
Florfenicol SCHEMBL4421631 0.95 LMNA (0.90) LMNACYP3A4MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13950 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075462-A Application of alpha-ketoglutaric acid in preparation of drugs for enhancing sensitivity of aquatic pathogenic bacteria to florfenicol 2026-05-26 CN claimed
CN-122075719-A Neuraminidase-ROS dual-response nano-carrier as well as preparation method and application thereof 2026-05-26 CN claimed
CN-224285299-U Drying equipment is used in florfenicol powder production SHANDONG HUACHEN PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-224272109-U Screening device for florfenicol powder production SHANDONG HUACHEN PHARMACEUTICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122056870-A Florfenicol preparation for reversing drug resistance and preparation method thereof 飞默(南阳)生物科技有限公司 2026-05-19 CN claimed
CN-122038211-A Hafnia alvei strain and application thereof 江西省农业科学院畜牧兽医研究所 2026-05-15 CN claimed
CN-122036889-A Cyclized antibacterial peptide CycP-1 of targeted multi-drug resistant klebsiella pneumoniae, composition and application thereof 湖北江夏实验室 2026-05-15 CN claimed
CN-115252821-B Preparation method of soluble florfenicol powder 成都科宏达化学有限责任公司 2026-05-15 CN claimed
CN-122035988-A Iron-sulfur-carbon-based composite filler for removing florfenicol in tail water 郑州大学 2026-05-15 CN claimed
CN-121286604-B Feed additive for regulating intestinal microecology to eliminate antibiotic residues 湖南坤源生物科技有限公司 2026-05-12 CN claimed
WO-1995030672-A1 AZIRIDINE COMPOUNDS, METHODS OF PREPARATION AND REACTIONS THEREOF DREXEL UNIVERSITY (US) 1995-11-16 WO claimed
EP-0674618-A1 ASYMMETRIC PROCESS FOR PREPARING FLORFENICOL, THIAMPHENICOL, CHLORAMPHENICOL AND OXAZOLINE INTERMEDIATES SCHERING CORPORATION (US) 1995-10-04 EP claimed
EP-0546018-B1 PHARMACEUTICAL COMPOSITION OF FLORFENICOL SCHERING CORP (US) 1994-10-19 EP claimed
US-5352832-A Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates SCHERING CORPORATION (US) 1994-10-04 US claimed
US-5346828-A Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase CELGENE CORPORATION (US) 1994-09-13 US claimed
WO-1994014764-A1 ASYMMETRIC PROCESS FOR PREPARING FLORFENICOL, THIAMPHENICOL, CHLORAMPHENICOL AND OXAZOLINE INTERMEDIATES SCHERING CORPORATION (US) 1994-07-07 WO claimed
EP-0546018-A1 PHARMACEUTICAL COMPOSITION OF FLORFENICOL. SCHERING CORP (US) 1993-06-16 EP claimed
EP-0507153-A2 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids CELGENE CORPORATION (US) 1992-10-07 EP claimed
WO-1992004016-A1 PHARMACEUTICAL COMPOSITION OF FLORFENICOL SCHERING CORPORATION (US) 1992-03-19 WO claimed
US-5082863-A Bactericide, veterinary use SCHERING CORPORATION (US) 1992-01-21 US claimed