Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.51 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.51 |
| ▸ | RPS17 | P08708 | 1/20 | 0.51 |
| ▸ | RPSA | P08865 | 1/20 | 0.51 |
| ▸ | RPS2 | P15880 | 1/20 | 0.51 |
| ▸ | RPL35A | P18077 | 1/20 | 0.51 |
| ▸ | RPL7 | P18124 | 1/20 | 0.51 |
| ▸ | RPL17 | P18621 | 1/20 | 0.51 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.51 |
| ▸ | RPS3 | P23396 | 1/20 | 0.51 |
| ▸ | RPS12 | P25398 | 1/20 | 0.51 |
| ▸ | RPL13 | P26373 | 1/20 | 0.51 |
| ▸ | RPL10 | P27635 | 1/20 | 0.51 |
| ▸ | RPL12 | P30050 | 1/20 | 0.51 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Florfenicol SCHEMBL49425 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL651770 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL3637832 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL29833609 | 1.00 | LMNA (1.00) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL4634861 | 0.99 | LMNA (0.97) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL650814 | 0.97 | LMNA (0.95) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL3817292 | 0.97 | LMNA (0.95) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL648260 | 0.96 | LMNA (0.93) | LMNACYP3A4MEN1KMT2ATSHR | |
| SCHEMBL12683654 | 0.96 | LMNA (0.93) | LMNACYP3A4MEN1KMT2ATSHR | |
| Florfenicol SCHEMBL4421631 | 0.95 | LMNA (0.90) | LMNACYP3A4MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710225-B | Delivery and retention of active agents within the skin | 范德生物公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-3133061-B1 | FLORFENICOL SYNTHESIZING METHOD | MASTEAM BIO TECH CO LTD (CN) | 2024-03-20 | — | — | EP | disclosed |
| US-20220175819-A1 | DELIVERY AND RETENTION OF ACTIVE AGENTS WITHIN THE SKIN | FOUNT BIO, INC. | 2022-06-09 | — | — | US | disclosed |
| US-9951000-B2 | Florfenicol synthesizing method | MASTEAM BIO TECH CO LTD (CN) | 2018-04-24 | — | — | US | disclosed |
| US-9951000-B2 | Florfenicol synthesizing method | MASTEAM BIO TECH CO LTD (CN) | 2018-04-24 | — | — | US | disclosed |
| US-9951000-B2 | Florfenicol synthesizing method | MASTEAM BIO TECH CO LTD (CN) | 2018-04-24 | — | — | US | disclosed |
| US-20170258930-A1 | SKIN PENETRATING PEPTIDES (SPPS) AND METHODS OF USE THEREFOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-14 | — | — | US | disclosed |
| US-20170173173-A1 | Skin Permeating and Cell Entering (SPACE) Peptides and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-06-22 | — | — | US | disclosed |
| EP-3133061-A1 | FLORFENICOL SYNTHESIZING METHOD | Masteam Bio-tech Co. Ltd. (CN) | 2017-02-22 | — | — | EP | disclosed |
| US-20160318859-A1 | FLORFENICOL SYNTHESIZING METHOD | MASTEAM BIO-TECH CO. LTD. | 2016-11-03 | — | — | US | disclosed |
| US-20150025221-A1 | Skin Permeating and Cell Entering (SPACE) Peptides and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-01-22 | — | — | US | disclosed |
| US-20140227174-A1 | SKIN PERMEATING AND CELL ENTERING (SPACE) PEPTIDES AND METHODS OF USE THEREFOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-14 | — | — | US | disclosed |
| US-8791062-B2 | Skin permeating and cell entering (SPACE) peptides and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-29 | — | — | US | disclosed |
| US-20140161871-A1 | SKIN PERMEATING AND CELL ENTERING (SPACE) PEPTIDES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-12 | — | — | US | disclosed |
| US-8518871-B2 | Skin permeating and cell entering (SPACE) peptides and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120128756-A1 | Skin Permeating And Cell Entering (SPACE) Peptides and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-05-24 | — | — | US | disclosed |
| US-8084643-B2 | Nitrogen-containing esters of the secondary alcohol group of florfenicol and of its analogs,including salts; veterinary medicine; nonhydrolyzing as needed to maintain the prodrug in aqueous solution in the subjects system until appropriate; cattle drinking water; bovine respiratory disease | INTERVET INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100210851-A1 | PROCESS FOR PREPARING OXAZOLIDINE- AND OXAZOLIDINONE-AMINODIOLS | INTERVET, INC. | 2010-08-19 | — | — | US | disclosed |
| US-20090170954-A1 | Process for Recovering Florfenicol and Florfenicol Analogs | SCHERING-PLOUGH LTD. (CH) | 2009-07-02 | — | — | US | disclosed |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175819-A1 | DELIVERY AND RETENTION OF ACTIVE AGENTS WITHIN THE SKIN | MMP8, MMP7, MMP1 | LMNA 928/4885CYP3A4 4437/4885MEN1 4375/4885 |
| US-20080188556-A1 | Water-Soluble Prodrugs of Florfenicol and its Analogs | PFAS, ADH5, SI | LMNA 2524/4885CYP3A4 15/4885MEN1 2179/4885 |
| US-20160318859-A1 | FLORFENICOL SYNTHESIZING METHOD | CYP2C19, DDC, CYP3A4 | LMNA 3913/4885CYP3A4 3/4885MEN1 3747/4885 |
| US-20100210851-A1 | PROCESS FOR PREPARING OXAZOLIDINE- AND OXAZOLIDINONE-AMINODIOLS | OXA1L, AZI2, CYP4F2 | LMNA 1521/4885CYP3A4 22/4885MEN1 1598/4885 |
| US-20090170954-A1 | Process for Recovering Florfenicol and Florfenicol Analogs | FDPS, FAU, PFAS | LMNA 3693/4885CYP3A4 11/4885MEN1 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.