Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633277 | 0.82 | CACNA1G (0.50) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL3752436 | 0.82 | CACNA1G (0.50) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4804451 | 0.77 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4804471 | 0.77 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4804476 | 0.77 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4804462 | 0.77 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4683069 | 0.76 | CYP2D6 (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6C5AR1 | |
| SCHEMBL8111309 | 0.75 | ALDH1A1 (0.57) | OPRM1TACR1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10831250 | 0.74 | TNF (0.60) | TNFALDH1A1KDM4EL3MBTL1GAA | |
| Oxalic Acid SCHEMBL5778359 | 0.74 | CACNA1G (0.68) | CACNA1GCACNA1HOPRM1TACR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |