Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804476 | 0.86 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4804471 | 0.86 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4675596 | 0.84 | CYP3A4 (0.40) | CACNA1GCACNA1HOPRM1CYP3A4OPRL1 | |
| SCHEMBL4681956 | 0.82 | OPRL1 (0.48) | CACNA1GCACNA1HOPRM1OPRL1C5AR1 | |
| SCHEMBL4804462 | 0.82 | CACNA1G (0.43) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL4674536 | 0.79 | PTGDR2 (0.35) | CACNA1GCACNA1HOPRM1OPRL1C5AR1 | |
| SCHEMBL3633277 | 0.79 | CACNA1G (0.50) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL3752436 | 0.79 | CACNA1G (0.50) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL3637945 | 0.77 | CACNA1G (0.57) | CACNA1GCACNA1HOPRM1TACR1TNF | |
| SCHEMBL3803735 | 0.76 | OPRM1 (0.49) | OPRM1OPRL1CYP2D6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |