Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13766425 | 0.82 | SMN1; SMN2 (0.57) | ADORA2AKHKKMT2ARAB9ANPC1 | |
| SCHEMBL2029199 | 0.81 | EPHX2 (0.61) | ADORA2AKHKKMT2ARAB9ANPC1 | |
| SCHEMBL7259516 | 0.81 | EPHX2 (0.61) | ADORA2AKHKKMT2ARAB9ANPC1 | |
| SCHEMBL13762191 | 0.81 | ADORA2A (0.53) | ADORA2AKHKKMT2ARAB9ANPC1 | |
| SCHEMBL7738145 | 0.80 | MITF (0.54) | ADORA2AKHKRORCKMT2ARAB9A | |
| SCHEMBL3637312 | 0.78 | RAB9A (0.50) | KHKRORCKMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL31148097 | 0.77 | ULK1 (0.50) | KMT2AMEN1TGM2HTTNPSR1 | |
| Acetic Acid SCHEMBL27852928 | 0.74 | POLB (0.56) | KMT2A | |
| SCHEMBL13766292 | 0.73 | SMN1; SMN2 (0.58) | KHKKMT2ANPC1EPHX2MAPK1 | |
| SCHEMBL2096759 | 0.73 | EPHX1 (0.48) | ADORA2AKHKKMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164491-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | Euroscreen S.A. (BE) | 2010-03-24 | — | — | EP | disclosed |
| WO-2009010477-A1 | PIPERIDINE-4-ACETIC ACID DERIVATIVES AND THEIR USE | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |