Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | MARK3 | P27448 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1153401 | 0.84 | GSK3B (0.36) | GSK3BCDK4CCND1CDK2PLK4 | |
| SCHEMBL1153528 | 0.84 | GSK3B (0.37) | GSK3BCDK4CCND1CDK2ALDH1A1 | |
| SCHEMBL5116268 | 0.84 | GAA (0.33) | GAA | |
| SCHEMBL1153041 | 0.82 | ALDH1A1 (0.33) | ALDH1A1GAA | |
| SCHEMBL1814326 | 0.76 | NPC1 (0.35) | ALDH1A1GAAPDE3BPDE3A | |
| SCHEMBL4427953 | 0.72 | CRHBP (0.40) | ALDH1A1 | |
| SCHEMBL342154 | 0.71 | HCRTR1 (0.36) | — | |
| SCHEMBL3176743 | 0.69 | — | — | |
| SCHEMBL5429034 | 0.69 | DPP4 (0.37) | — | |
| SCHEMBL3001186 | 0.68 | KMT2A (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155673-A2 | 3-(2-ALKOXY-PHENYL)-SUBSTITUTED TETRAMATES | Bayer CropScience AG (DE) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008138551-A2 | 3-(2-ALKOXY-PHENYL)-SUBSTITUTED TETRAMATES | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | WO | disclosed |