Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.35 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000246 | 0.84 | HSD11B1 (0.36) | HCRTR1HCRTR2ALDH1A1POLBCA12 | |
| SCHEMBL4428134 | 0.84 | CRHBP (0.37) | CRHBPCRHR2HTTCACNG8GRIA1 | |
| SCHEMBL15001062 | 0.74 | CRHBP (0.43) | CRHBPCRHR2CACNG8GRIA1HCRTR1 | |
| SCHEMBL1153528 | 0.74 | GSK3B (0.37) | ALDH1A1POLB | |
| SCHEMBL342154 | 0.74 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL15001063 | 0.73 | CRHBP (0.45) | CRHBPCRHR2HCRTR1HCRTR2DRD1 | |
| SCHEMBL11228395 | 0.73 | CRHBP (0.38) | CRHBPCRHR2PDE7AHCRTR1HCRTR2 | |
| SCHEMBL3640338 | 0.72 | GSK3B (0.39) | ALDH1A1 | |
| SCHEMBL11224539 | 0.71 | CRHBP (0.43) | CRHBPCRHR2HCRTR1HCRTR2 | |
| SCHEMBL10500029 | 0.70 | CA2 (0.53) | CRHBPCRHR2CACNG8GRIA1CACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741700-B1 | 1-H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES AS PEST-CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2009-10-07 | — | — | EP | disclosed |
| EP-0741700-A1 | 1-H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995020572-A1 | 1-H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-03 | — | — | WO | disclosed |